Estimating disease prevalence in large datasets using genetic risk scores
oleh: Benjamin D. Evans, Piotr Słowiński, Andrew T. Hattersley, Samuel E. Jones, Seth Sharp, Robert A. Kimmitt, Michael N. Weedon, Richard A. Oram, Krasimira Tsaneva-Atanasova, Nicholas J. Thomas
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Estimating disease prevalence in biobanks is prone to error, especially for self-reported traits. Here, the authors propose a method to estimate the prevalence of a disease within a cohort based on genetic risk scores.