(2R)-8-Benzyl-2-[(S)-hydroxy(phenyl)methyl]-8-azabicyclo[3.2.1]octan-3-one
oleh: Krzysztof Brzezinski, Ryszard Lazny, Michal Sienkiewicz, Sławomir Wojtulewski, Zbigniew Dauter
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2012-01-01 |
Deskripsi
The crystal of the title compound, C21H23NO2, was chosen from a conglomerate formed by a racemic mixture. An intramolecular hydrogen bond is formed between hydroxy group and heterocyclic N atom of the azabicyclo[3.2.1]octan-3-one system. The crystal structure is stabilized by C—H...O interactions between aliphatic C—H groups and the carbonyl O atom. For the title chiral crystal, the highly redundant and accurate diffraction data set collected with low energy copper radiation gave a Flack parameter of 0.12 (18) for anomalous scattering effects originating from O atoms.