Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls

oleh: Hui Yang, Huai-Ri Sun, Rui-Qing He, Le Yu, Wei Hu, Jie Chen, Sen Yang, Gong-Gu Zhang, Ling Zhou

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

There is great interest in methods for catalytic enantioselective construction of axially chiral compounds found in natural products. Here, the authors develop a cycloaddition strategy for atroposelective construction of indole-based biaryls via chiral phosphoric acid-catalysed cycloaddition.