Mechanical homeostasis of liver sinusoid is involved in the initiation and termination of liver regeneration
oleh: Jun Ishikawa, Makoto Takeo, Ayako Iwadate, Junko Koya, Miho Kihira, Masamitsu Oshima, Yuki Suzuki, Kazushi Taniguchi, Ayaka Kobayashi, Takashi Tsuji
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
Ishikawa, Takeo et al. present a 3D liver sinusoidal network analysis method and identify important parameters after partial hepatectomy. They find that in coordination with cytokine networks, mechanical homeostatic signalling, including shear stress and tension, plays critical roles in the initiation and termination of liver organ regeneration.