Risk Factors for Development and Severity of COVID-19 in COPD Patients
oleh: Matteo Bonato, Matteo Bonato, Umberto Semenzato, Mariaenrica Tinè, Erica Bazzan, Marco Damin, Davide Biondini, Alvise Casara, Micaela Romagnoli, Graziella Turato, Manuel G. Cosio, Manuel G. Cosio, Marina Saetta, Simonetta Baraldo
| Format: | Article |
|---|---|
| Diterbitkan: | Frontiers Media S.A. 2021-08-01 |
Deskripsi
The impact that COVID-19 could have on patients with COPD is a real concern. In this study we evaluated, in a cohort of longitudinally followed COPD subjects, the incidence of COVID-19, seeking for possible risk factors and prognostic factors predicting the clinical outcome. In our cohort of 370 patients (followed for 5.3 ± 2.7 years), 22 developed COVID-19 (COPD/COVID-19+) between February/November 2020 (5.9%). Cardio-metabolic conditions (hypertension, dyslipidemia, obesity, diabetes) but not respiratory abnormalities (FEV1, DLCO, emphysema and exacerbation history), were risk factors for development of COVID-19 in COPD patients. Out of the 22 COPD/COVID-19+ patients, 10 needed intensive care. Low DLCO and emphysema, but also metabolic comorbidities, were related to the need for intensive care.