Subtomogram averaging of COPII assemblies reveals how coat organization dictates membrane shape
oleh: Joshua Hutchings, Viktoriya Stancheva, Elizabeth A. Miller, Giulia Zanetti
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2018-10-01 |
Deskripsi
The COPII coat assembles in two concentric layers and mediates protein export from the endoplasmic reticulum. Here the authors present the 4.9 Å resolution cryo-tomography and subtomogram averaging structure of the membrane bound COPII inner coat that was obtained by in vitro reconstitution and discuss mechanistic implications.