A strategy to discover new organizers identifies a putative heart organizer
oleh: Claire Anderson, Mohsin A. F. Khan, Frances Wong, Tatiana Solovieva, Nidia M. M. Oliveira, Richard A. Baldock, Cheryll Tickle, Dave W. Burt, Claudio D. Stern
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-08-01 |
Deskripsi
Organizers are regions in the embryo that induce cell fate and impart pattern on neighbouring regions. Here, the authors search for new organizers based on a common gene signature, and show that the Anterior Intestinal Portal endoderm induces cardiac identity, specifies ventricle and inhibits atrial character.