Whole-Genome Sequencing of Drug-Resistant Mycobacterium tuberculosis Strains, Tunisia, 2012–2016
oleh: Imen Bouzouita, Andrea Maurizio Cabibbe, Alberto Trovato, Henda Daroui, Asma Ghariani, Basma Midouni, Leila Essalah, Emna Mehiri, Daniela Maria Cirillo, Leila Slim Saidi
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2019-03-01 |
Deskripsi
To investigate transmission of drug-resistant strains of Mycobacterium tuberculosis in Tunisia, we performed whole-genome sequencing on 46 multidrug-resistant strains isolated during 2012–2016. Core-genome multilocus sequence typing grouped 30 strains (65.2%) into 3 clusters, indicating extensive recent transmission and Haarlem clone predominance. Whole-genome sequencing might help public health services undertake appropriate control actions.