Re-infection with a different SARS-CoV-2 clade and prolonged viral shedding in a hematopoietic stem cell transplantation patient
oleh: Abeer N. Alshukairi, Sherif A. El-Kafrawy, Ashraf Dada, Muhammad Yasir, Amani H. Yamani, Mohammed F. Saeedi, Ahmed Aljohaney, Naif I. AlJohani, Husam A. Bahaudden, Intikhab Alam, Takashi Gojobori, Aleksandar Radovanovic, Thamir A. Alandijany, Norah A. Othman, Tagreed L. Alsubhi, Ahmed M. Hassan, Ahmed M. Tolah, Jaffar A. Al-Tawfiq, Alimuddin Zumla, Esam I Azhar
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2021-09-01 |
Deskripsi
Immunocompromised patients who have a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection pose many clinical and public health challenges. We describe the case of a hematopoietic stem cell transplantation patient with lymphoma who had a protracted illness requiring three consecutive hospital admissions. Whole genome sequencing confirmed two different SARS-CoV-2 clades. Clinical management issues and the unanswered questions arising from this case are discussed.