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AIM: To evaluate the long-term results of visual outcomes and safety of phacovitrectomy with intraocular lens implantation in the treatment of complex vitreoretinal diseases. <p>METHODS: A retrospective analysis was performed in case series. Totally 143 eyes of 162 patients underwent phacovitrectomy and intraocular lens implantation. Main outcome measures were visual acuity and operative complications.<p>RESULTS: The mean follow-up was 26.2mo. The main vitreoretinal surgical indications were retinal detachment, proliferative diabetic retinopathy and macula disease. In total, 86 eyes(53.1%), 89 eyes(54.9%), 87 eyes(53.7%), 93 eyes(57.2%)and 101 eyes(62.3%)gained two or more lines of vision compared with baseline, at 1mo, 6mo, 12mo, 18mo and 24mo follow-up.<p>CONCLUSION:Phacovitrectomy and intraocular lens implantation is safely and effectively used for cataracts and complex vitreoretinal diseases.