LITESEC-T3SS - Light-controlled protein delivery into eukaryotic cells with high spatial and temporal resolution
oleh: Florian Lindner, Bailey Milne-Davies, Katja Langenfeld, Thorsten Stiewe, Andreas Diepold
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-05-01 |
Deskripsi
The type III secretion system (T3SS) of bacteria can be used to inject cargo into eukaryotic cells but its lack of target specificity is a disadvantage. Here the authors place the T3SS under the regulation of light by engineering optogenetic switches into the dynamic cytosolic T3SS component SctQ.