Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc

oleh: Shinya Matsuda, Jonas V. Schaefer, Yusuke Mii, Yutaro Hori, Dimitri Bieli, Masanori Taira, Andreas Plückthun, Markus Affolter

Format: Article
Diterbitkan: Nature Portfolio 2021-11-01

Deskripsi

Morphogens disperse to pattern tissues and control their growth during development, allowing for the specification of multiple fates across space. Here the authors block dispersal of a morphogen Dpp (BMP2/4) and show that the requirement for Dpp dispersal is much lower than previously thought.