CK2-induced cooperation of HHEX with the YAP-TEAD4 complex promotes colorectal tumorigenesis

oleh: Yuegui Guo, Zhehui Zhu, Zhenyu Huang, Long Cui, Wei Yu, Wanjin Hong, Zhaocai Zhou, Peng Du, Chen-Ying Liu

Format: Article
Diterbitkan: Nature Portfolio 2022-08-01

Deskripsi

Hippo signalling is often deregulated in cancers. Here the authors show that CK2 enhances the cooperation of HHEX with YAP-TEAD complex to promote colorectal tumorigenesis.