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This study aimed to investigate the efficiency of submerged membrane bioreactors (SMBR) in textile and municipal wastewater treatment. First, membrane bioreactors were designed and fabricated using hollow fiber polypropylene membranes with pores of 0.2 μm on a pilot scale with a volume of 100 liters. Then, for 20 days, activated sludge was formed and municipal wastewater was treated. For 28 days, incremental percentages of 20%, 40% 60%, and 80% of textile wastewater were gradually added to municipal wastewater. Finally, for 10 days, the sewage of the textile wool factory was examined. Pilot performance for municipal wastewater at the maximum concentration of MLSS mg/L 2310, percentages of removal of biological parameters COD, BOD, TSS, VSS equal to 94.65%, 96.03%, 96.72%, 95.58%, for mixed wastewater, respectively Urban and textile in MLSS equal to 2920 mg/L, 94.1%, 95.2%, 97%, 95.9% have been reported, respectively. Finally, for textile wastewater with the hydraulic retention time of 25 hours, the sludge retention time of 25 days with MLSS equal to 1370 mg/L, the studied parameters along with color and turbidity were 95.1%, 95.8%, 96.6%, 95%, 93%, 99.8%, respectively. This study showed that SMBR can be used as an efficient method for textile and municipal wastewater treatment.