Minutes-timescale 3D isotropic imaging of entire organs at subcellular resolution by content-aware compressed-sensing light-sheet microscopy
oleh: Chunyu Fang, Tingting Yu, Tingting Chu, Wenyang Feng, Fang Zhao, Xuechun Wang, Yujie Huang, Yusha Li, Peng Wan, Wei Mei, Dan Zhu, Peng Fei
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
High resolution imaging of large biological volumes typically takes a long time from hours to days. Here the authors use a Bessel light-sheet approach combined with a content-aware compressed sensing computational pipeline to image whole mouse organs at subcellular resolution in a few minutes.