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According to the analysis of cerebrospnial fluid (CSF) cytological examination (by slide centrifugation) results of 15 940 central nervous system infectious cases, this cytologic examination method shows definite diagnostic values as follows: 1) better etiological diagnostic value for central nervous system infectious diseases, such as purulent, viral, tuberculous, fungus and parasitic encephalitis meningitis and meningoencephalitis; 2) better differential diagnostic value for acute infectious toxic encephalopathy, meningeal carcinomatosis and central nervous system non⁃infectious diseases such as tumorous, leukemic and hemorrhagic meningoencephalitis and encephalopathy; 3) better clinical value for severity monitoring and prognostic judgement of central nervous system infectious diseases. <br />