The WDR11 complex facilitates the tethering of AP-1-derived vesicles

oleh: Paloma Navarro Negredo, James R. Edgar, Paul T. Manna, Robin Antrobus, Margaret S. Robinson

Format: Article
Diterbitkan: Nature Portfolio 2018-02-01

Deskripsi

Trafficking from endosomes to the trans-Golgi network requires recognition of vesicle tethers during membrane docking. Here, the authors identify a complex localised to AP-1 generated vesicles containing WDR11, C17orf75 and FAM91A, which together with TBC1D23 facilitates vesicle capture on Golgi membranes