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The immune factors driving DNA methylation variation in human blood
oleh: Jacob Bergstedt, Sadoune Ait Kaci Azzou, Kristin Tsuo, Anthony Jaquaniello, Alejandra Urrutia, Maxime Rotival, David T. S. Lin, Julia L. MacIsaac, Michael S. Kobor, Matthew L. Albert, Darragh Duffy, Etienne Patin, Lluís Quintana-Murci, Milieu Intérieur Consortium
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-10-01 |
Deskripsi
Many studies assess epigenetic marks in white blood cells, but it is unclear how much immune factors affect the epigenome. Here, the authors show that fine-scale blood cell composition and cytomegalovirus infection affect the DNA methylome of adults.