N 6-methyladenosine of Spi2a attenuates inflammation and sepsis-associated myocardial dysfunction in mice
oleh: Xiangyu Wang, Yan Ding, Ran Li, Rujun Zhang, Xuejun Ge, Ruifang Gao, Miao Wang, Yubing Huang, Fang Zhang, Bin Zhao, Wang Liao, Jie Du
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
N6-methyladenosine (m6A) methylation of RNA is a common type of RNA modification that regulates gene expression. Here, the authors report m6A methylation of serpin 2 A negatively regulates inflammation and reduces heart dysfunction in the setting of sepsis.