Bowen's Disease Associated With Two Human Papilloma Virus Types

oleh: Hojat Eftekhari, Kaveh Gharaei Nejad, Seyyede Zeinab Azimi, Rana Rafiei, Alireza Mesbah

Format: Article
Diterbitkan: Tehran University of Medical Sciences 2017-10-01

Deskripsi

Bowen's disease (BD) is an epidermal in-situ squamous cell carcinoma (SCC). Most Human Papilloma Viruses (HPV)-positive lesions in Bowen's disease are localized to the genital region or distal extremities (periungual sites) in which HPV type-16 is frequently detected. Patient was a 64-year-old construction worker for whom we detected 2 erythematous psoriasiform reticular scaly plaques on peri-umbilical and medial knee. Biopsy established the diagnosis of Bowen's disease and polymerase chain reaction assay showed HPV-6, -18 co-infection. Patient was referred for surgical excision.