Find in Library

By means of gas-liquid chromatographic analysis, coprostanol excretion has been studied in rats fed diets containing either no fat or varying amounts of linoleic acid, palmitic acid, or oleic acid. Coprostanol excretion was accelerated by linoleic acid, and depressed by oleic and palmitic acids. The acceleration of coprostanol formation by linoleic acid was demonstrated to occur in the large intestine. In these experiments cholesterol and coprostanol were the only neutral excretion products of cholesterol-4-C14.