4-(3-Fluorophenyl)-6-hydroxy-5-(thiophen-2-ylcarbonyl)-6-trifluoromethyl-1,3-diazinan-2-one
oleh: Qin He, Jing Li, Bao-Jun Huang
| Format: | Article |
|---|---|
| Diterbitkan: | International Union of Crystallography 2011-04-01 |
Deskripsi
In the title compound, C16H12F4N2O3S, the pyrimidine ring adopts a half-chair conformation; the mean plane formed by the ring atoms excluding the C atom bonded to the thiophen-2-ylcarbonyl group has an r.m.s. deviation of 0.059 Å. The dihedral angle between the benzene and thiophene rings is 62.26 (7)°. The molecular conformation is stabilized by an intramolecular O—H...O hydrogen bond, generating an S(6) ring. In the crystal, adjacent molecules are connected via a centrosymmetric R22(6) motif, formed by N—H...O hydrogen bonds.