A Cdc42-mediated supracellular network drives polarized forces and Drosophila egg chamber extension
oleh: Anna Popkova, Orrin J. Stone, Lin Chen, Xiang Qin, Chang Liu, Jiaying Liu, Karine Belguise, Denise J. Montell, Klaus M. Hahn, Matteo Rauzi, Xiaobo Wang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-04-01 |
Deskripsi
During development, organs undergo large scale forces driven by the cytoskeleton but the precise molecular regulation of cytoskeletal networks remains unclear. Here, the authors report a Cdc42-dependent supracellular cytoskeletal network integrates local actomyosin contraction at tissue scale and drives global tissue elongation.