A New Antiplasmodial Compound from the Papuan Marine Sponge Xestospongia sp.
oleh: Murtihapsari Murtihapsari, Amir M Suruwaky, Kadarusman Kadarusman, Dikdik Kurnia, Tati Herlina, Unang Supratman
| Format: | Article |
|---|---|
| Diterbitkan: | Syarif Hidayatullah Jakarta State Islamic University 2018-05-01 |
Deskripsi
A new antiplasmodial compound, 2-(3H-diazirine-3-yl)benzaldehyde (1), has been isolated from the Papuan marine sponge Xestospongia sp. The structure elucidation of compound 1 was determined by spectroscopic evidences including UV, IR, MS, 1D and 2D-NMR analysis. Compound 1 showed moderate antiplasmodial activity against Plasmodium falciparum with IC50 value of 1.08 x 10-6 mM. DOI:http://dx.doi.org/10.15408/jkv.v4i1.6735