Co-option of the cardiac transcription factor Nkx2.5 during development of the emu wing
oleh: Peter G. Farlie, Nadia M. Davidson, Naomi L. Baker, Mai Raabus, Kelly N. Roeszler, Claire Hirst, Andrew Major, Mylene M. Mariette, David M. Lambert, Alicia Oshlack, Craig A. Smith
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-07-01 |
Deskripsi
The transcription factor Nkx2.5 is essential for heart development. Here, the authors identify a previously unknown expression domain for Nkx2.5 in the emu wing and explore its role in diminished wing bud development in the flightless emu, compared with three other birds that have functional wings.