Structural and mechanistic characterization of an archaeal-like chaperonin from a thermophilic bacterium
oleh: Young Jun An, Sara E. Rowland, Jung-Hyun Na, Dario Spigolon, Seung Kon Hong, Yeo Joon Yoon, Jung-Hyun Lee, Frank T. Robb, Sun-Shin Cha
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-10-01 |
Deskripsi
Chaperonins (CPNs) are ATP-dependent protein-folding machines. Here the authors present the open and closed crystal structures of a Group III CPN from the thermophilic bacterium Carboxydothermus hydrogenoformans, discuss its mechanism and structurally compare it with Group I and II CPNs.