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Racial/Ethnic Disparities in Exposure, Disease Susceptibility, and Clinical Outcomes during COVID-19 Pandemic in National Cohort of Adults, United States
oleh: McKaylee M. Robertson, Meghana G. Shamsunder, Ellen Brazier, Mekhala Mantravadi, Rebecca Zimba, Madhura S. Rane, Drew A. Westmoreland, Angela M. Parcesepe, Andrew R. Maroko, Sarah G. Kulkarni, Christian Grov, Denis Nash
Format: | Article |
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Diterbitkan: | Centers for Disease Control and Prevention 2022-11-01 |
Deskripsi
We examined racial/ethnic disparities for COVID-19 seroconversion and hospitalization within a prospective cohort (n = 6,740) in the United States enrolled in March 2020 and followed-up through October 2021. Potential SARS-CoV-2 exposure, susceptibility to COVID-19 complications, and access to healthcare varied by race/ethnicity. Hispanic and Black non-Hispanic participants had more exposure risk and difficulty with healthcare access than white participants. Participants with more exposure had greater odds of seroconversion. Participants with more susceptibility and more barriers to healthcare had greater odds of hospitalization. Race/ethnicity positively modified the association between susceptibility and hospitalization. Findings might help to explain the disproportionate burden of SARS-CoV-2 infections and complications among Hispanic/Latino/a and Black non-Hispanic persons. Primary and secondary prevention efforts should address disparities in exposure, vaccination, and treatment for COVID-19.