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Histology and regional distribution of the stratum lucidum of the epidermis in Large White Yorkshire pigs were studied using 12 animals of six to fen months of age. Skin samples of 2 cmz area were collected immediately following exsanguination from eight areas of the body viz., the snout, dorsal nasal, dorsal neck, ventral neck, dorsal abdomen, lateral abdomen, ventral abdomen and carpal regions. Stratum lucidum appeared as a clear, bright, homogenous, strongly eosinophilic layer consisting of flattened, compact, eosinophilic cells without clear cell boundaries and the nucleus. A definite stratum lucidum was seen only in the snout, dorsal nasal and ventral abdominal areas.