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Abstract Background Melanosis coli is a benign condition characterized by deposition of lipofuscin in colonic mucosa due to long-term laxative use. Case presentation Here I am reporting a case of an 85-year-old man who presented with constipation, with a history of long-term herbal medication intake as laxatives, and upon evaluation, he was found to have melanosis coli. Conclusion Melanosis coli is a common adverse effect of chronic laxative use which is more common in elderly population with constipation.