Role of proprioceptors in chronic musculoskeletal pain

oleh: Cheng‐Han Lee, Chih‐Cheng Chen

Format: Article
Diterbitkan: Wiley 2024-01-01

Deskripsi

Abstract Proprioceptors are non‐nociceptive low‐threshold mechanoreceptors. However, recent studies have shown that proprioceptors are acid‐sensitive and express a variety of proton‐sensing ion channels and receptors. Accordingly, although proprioceptors are commonly known as mechanosensing neurons that monitor muscle contraction status and body position, they may have a role in the development of pain associated with tissue acidosis. In clinical practice, proprioception training is beneficial for pain relief. Here we summarize the current evidence to sketch a different role of proprioceptors in ‘non‐nociceptive pain’ with a focus on their acid‐sensing properties.