Endophilin-A coordinates priming and fusion of neurosecretory vesicles via intersectin
oleh: Sindhuja Gowrisankaran, Sébastien Houy, Johanna G. Peña del Castillo, Vicky Steubler, Monika Gelker, Jana Kroll, Paulo S. Pinheiro, Dirk Schwitters, Nils Halbsgut, Arndt Pechstein, Jan R. T. van Weering, Tanja Maritzen, Volker Haucke, Nuno Raimundo, Jakob B. Sørensen, Ira Milosevic
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2020-03-01 |
Deskripsi
Endophilins-A are conserved membrane-associated proteins required for endocytosis. Here, the authors report that endophilins-A also promote exocytosis of neurosecretory vesicles by coordinating priming and fusion through intersectin-1, independently of their roles in different types of endocytosis.