Epigenetic models developed for plains zebras predict age in domestic horses and endangered equids
oleh: Brenda Larison, Gabriela M. Pinho, Amin Haghani, Joseph A. Zoller, Caesar Z. Li, Carrie J. Finno, Colin Farrell, Christopher B. Kaelin, Gregory S. Barsh, Bernard Wooding, Todd R. Robeck, Dewey Maddox, Matteo Pellegrini, Steve Horvath
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-12-01 |
Deskripsi
Larison et al. report epigenetic aging models in plains zebras (Equus quagga) using the epigenetic clock and epigenetic pacemaker approaches. Their epigenetic clock allows age to be accurately estimated in endangered sister species, and the pacemaker model identifies an association between inbreeding and accelerating aging.