A unified strategy toward total syntheses of lindenane sesquiterpenoid [4 + 2] dimers

oleh: Biao Du, Zhengsong Huang, Xiao Wang, Ting Chen, Guo Shen, Shaomin Fu, Bo Liu

Format: Article
Diterbitkan: Nature Portfolio 2019-04-01

Deskripsi

Of the 3 classes of dimeric lindenane sesquiterpenoids, only type I And II have been targeted in total synthesis. Here, the authors report a unified strategy to synthetically access the 3 classes of lindenane sesquiterpenoids dimers by developing a [4 + 2] cycloaddition between a common furyl diene and various dienophiles.