Synthesis and structural analysis of an asymmetric azacyclophane via Mannich cross macrocyclisation of l-tyrosine derivatives

oleh: Laura F. Leal, Sebastián Chaves, Rodolfo Quevedo

Format: Article
Diterbitkan: Elsevier 2023-01-01

Deskripsi

This article describes the synthesis of an asymmetric azacyclophane via a three-component (tyramine, l-tyrosine ethyl ester and formaldehyde) intermolecular hydrogen bond-assisted Mannich reaction.