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Synthesis and structural analysis of an asymmetric azacyclophane via Mannich cross macrocyclisation of l-tyrosine derivatives
oleh: Laura F. Leal, Sebastián Chaves, Rodolfo Quevedo
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2023-01-01 |
Deskripsi
This article describes the synthesis of an asymmetric azacyclophane via a three-component (tyramine, l-tyrosine ethyl ester and formaldehyde) intermolecular hydrogen bond-assisted Mannich reaction.