Find in Library
Search millions of books, articles, and more
Indexed Open Access Databases
A new mechanism for LKB1 activation
oleh: Szu-Wei Lee, Hui-Kuan Lin
Format: | Article |
---|---|
Diterbitkan: | Taylor & Francis Group 2018-05-01 |
Deskripsi
Liver kinase B1 (LKB1, also known as serine/threonine kinase 11, STK11) has been thought to be a constitutively active tumor suppressor that is activated by forming an active complex. Very recently, a new post-translational modification on LKB1 was identified that can regulate LKB1 activation and LKB1-mediated cancer cell survival under energy stress.