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A multi-marker association method for genome-wide association studies without the need for population structure correction
oleh: Jonas R. Klasen, Elke Barbez, Lukas Meier, Nicolai Meinshausen, Peter Bühlmann, Maarten Koornneef, Wolfgang Busch, Korbinian Schneeberger
Format: | Article |
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Diterbitkan: | Nature Portfolio 2016-11-01 |
Deskripsi
Currently available methods for phenotype to genetic markers association need to account for population structure. Here, Klasen et al. devise a statistical method called Quantitative Trait Cluster Association Test (QTCAT) that overcomes the need for population structure correction.