A multi-marker association method for genome-wide association studies without the need for population structure correction

oleh: Jonas R. Klasen, Elke Barbez, Lukas Meier, Nicolai Meinshausen, Peter Bühlmann, Maarten Koornneef, Wolfgang Busch, Korbinian Schneeberger

Format: Article
Diterbitkan: Nature Portfolio 2016-11-01

Deskripsi

Currently available methods for phenotype to genetic markers association need to account for population structure. Here, Klasen et al. devise a statistical method called Quantitative Trait Cluster Association Test (QTCAT) that overcomes the need for population structure correction.