Temporal Dynamics and Evolution of SARS-CoV-2 Demonstrate the Necessity of Ongoing Viral Genome Sequencing in Ontario, Canada
oleh: Calvin P. Sjaarda, Jennifer L. Guthrie, Samira Mubareka, Jared T. Simpson, Bettina Hamelin, Henry Wong, Leanne Mortimer, Robert Slinger, Andrew G. McArthur, Marc Desjardins, Allison McGeer, Tony Mazzulli, Katya Douchant, Danielle Brabant-Kirwan, Ramzi Fattouh, Aaron Campigotto, Samir N. Patel, Nahuel Fittipaldi, Robert I. Colautti, Prameet M. Sheth
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-06-01 |
Deskripsi
Genome-wide variation in SARS-CoV-2 reveals evolution and transmission dynamics which are critical considerations for disease control and prevention decisions. Here, we review estimates of the genome-wide viral mutation rates, summarize current COVID-19 case load in the province of Ontario, Canada (5 January 2021), and analyze published SARS-CoV-2 genomes from Ontario (collected prior to 24 November 2020) to test for more infectious genetic variants or lineages.