Cell specific photoswitchable agonist for reversible control of endogenous dopamine receptors

oleh: Prashant Donthamsetti, Nils Winter, Adam Hoagland, Cherise Stanley, Meike Visel, Stephan Lammel, Dirk Trauner, Ehud Isacoff

Format: Article
Diterbitkan: Nature Portfolio 2021-08-01

Deskripsi

In this study, the authors develop a photo-pharmacological strategy using a Membrane anchored Photoswitchable orthogonal remotely tethered agonist for the Dopamine receptor (MP-D) to selectively and reversibly modulate the D1R receptor subtype.