Extent of myosin penetration within the actin cortex regulates cell surface mechanics
oleh: Binh An Truong Quang, Ruby Peters, Davide A. D. Cassani, Priyamvada Chugh, Andrew G. Clark, Meghan Agnew, Guillaume Charras, Ewa K. Paluch
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-11-01 |
Deskripsi
Cellular deformations are largely driven by contractile forces generated by myosin motors in the submembraneous actin cortex. Here we show that these forces are controlled not simply by cortical myosin levels, but rather by myosins spatial arrangement, specifically the extent of their overlap with cortical actin.