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<i>bla</i>_IMP and <i>bla</i>_VIM are the most detected plasmid-encoded carbapenemase genes in <i>Pseudomonas aeruginosa</i>. Previous studies have reported plasmid sequences carrying <i>bla</i>_IMP variants, except <i>bla</i>_IMP-56. In this study, we aimed to characterize a plasmid carrying <i>bla</i>_IMP-56 in a <i>P. aeruginosa</i> strain isolated from a Mexican hospital. The whole genome of <i>P. aeruginosa</i> strain PE52 was sequenced using Illumina Miseq 2 × 150 bp, with 5 million paired-end reads. We characterized a 27 kb plasmid (pPE52IMP) that carried <i>bla</i>_IMP-56. The phylogenetic analysis of RepA in pPE52IMP and 33 <i>P. aeruginosa</i> plasmids carrying resistance genes reported in the GenBank revealed that pPE52IMP and four plasmids (pMATVIM-7, unnamed (FDAARGOS_570), pD5170990, and pMRVIM0713) were in the same clade. These closely related plasmids belonged to the MOB_P11 subfamily and had similar backbones. Another plasmid (p4130-KPC) had a similar backbone to pPE52IMP; however, its RepA was truncated. In these plasmids, the resistance genes <i>bla</i>_KPC-2, <i>bla</i>_VIM variants, <i>aac(6′)-Ib4</i>, <i>bla</i>_OXA variants, and <i>bla</i>_IMP-56 were inserted between <i>phd</i> and resolvase genes. This study describes a new family of plasmids carrying resistance genes, with a similar backbone, the same RepA, and belonging to the MOB_P11 subfamily in <i>P. aeruginosa</i>. In addition, our characterized plasmid harboring <i>bla</i>_IMP-56 (pPE52IMP) belongs to this family.