Single cell atlas of spinal cord injury in mice reveals a pro-regenerative signature in spinocerebellar neurons

oleh: Kaya J. E. Matson, Daniel E. Russ, Claudia Kathe, Isabelle Hua, Dragan Maric, Yi Ding, Jonathan Krynitsky, Randall Pursley, Anupama Sathyamurthy, Jordan W. Squair, Boaz P. Levi, Gregoire Courtine, Ariel J. Levine

Format: Article
Diterbitkan: Nature Portfolio 2022-09-01

Deskripsi

Matson et al. performed single nucleus sequencing of the “spared” spinal cord tissue distal to an injury in mice. They found that spinocerebellar neurons expressed a pro-regenerative gene signature and showed axon outgrowth after injury.