Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii

oleh: Ui Okada, Eiki Yamashita, Arthur Neuberger, Mayu Morimoto, Hendrik W. van Veen, Satoshi Murakami

Format: Article
Diterbitkan: Nature Portfolio 2017-11-01

Deskripsi

The tripartite multidrug efflux pump MacA-MacB-TolC in Gram-negative bacterial pathogens is driven by the ATPase MacB, which belongs to the ATP-binding cassette (ABC) superfamily. Here the authors present the 3.4 Å resolution crystal structure of MacB, and compare it with other known ABC transporter structures.