Deep learning modeling m6A deposition reveals the importance of downstream cis-element sequences
oleh: Zhiyuan Luo, Jiacheng Zhang, Jingyi Fei, Shengdong Ke
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-05-01 |
Deskripsi
The site specificity of m6A mRNA modification is a fundamental RNA biology question. Here, Luo et al., develop the iM6A, a deep learning method to model this process, showing that its site-specificity is determined by the primary nucleotide sequence.