Phase separation modulates the assembly and dynamics of a polarity-related scaffold-signaling hub
oleh: Wei Tan, Sihua Cheng, Yingying Li, Xiao-Yang Li, Ning Lu, Jingxian Sun, Guiyue Tang, Yujiao Yang, Kezhu Cai, Xuefei Li, Xijun Ou, Xiang Gao, Guo-Ping Zhao, W. Seth Childers, Wei Zhao
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
The polarization of distinct scaffold-signaling hubs at opposite cell poles constitutes the basis of asymmetric cell division. Here, the authors show that phase separation serves as a general mechanism to regulate the assembly and dynamics of a new-pole scaffold-signaling hub.