Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs

oleh: Christopher D. Scharer, Benjamin G. Barwick, Muyao Guo, Alexander P. R. Bally, Jeremy M. Boss

Format: Article
Diterbitkan: Nature Portfolio 2018-04-01

Deskripsi

During B cell differentiation, the role of different genomic loci in transcriptional and epigenetic regulation in vivo is not well defined. Here the authors use an in vivo B cell differentiation model to map cellular division-dependent cis-regulatory element road map with ATAC-seq.