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Anti-inflammatory benefits of semaglutide: State of the art
oleh: Habib Yaribeygi, Mina Maleki, Tannaz Jamialahmadi, Amirhossein Sahebkar
Format: | Article |
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Diterbitkan: | Elsevier 2024-06-01 |
Deskripsi
Individuals with diabetes often have chronic inflammation and high levels of inflammatory cytokines, leading to insulin resistance and complications. Anti-inflammatory agents are proposed to prevent these issues, including using antidiabetic medications with anti-inflammatory properties like semaglutide, a GLP-1 analogue. Semaglutide not only lowers glucose but also shows potential anti-inflammatory effects. Studies suggest it can modulate inflammatory responses and benefit those with diabetes. However, the exact mechanisms of its anti-inflammatory effects are not fully understood. This review aims to discuss the latest findings on semaglutide's anti-inflammatory effects and the potential pathways involved.