IL-34 a Newly Discovered Cytokine

oleh: M.L. Castellani, A. Anogeianaki, P. Felaco, E. Toniato, M.A. De Lutiis, B. Shaik, M. Fulcheri, J. Vecchiet, S. Tetè, V. Salini, T.C. Theoharides, A. Caraffa, P. Antinolfi, S. Frydas, P. Conti, C. Cuccurullo, C. Ciampoli, G. Cerulli

Format: Article
Diterbitkan: SAGE Publishing 2010-05-01

Deskripsi

In this study we describe some biological effects of IL-34, a newly discovered cytokine. We show that Il-34 stimulates monocyte cell viability and directly modulates the number and function of monocytes and regulates myeloid cell growth and differentiation. Moreover, since IL-34 in mice is involved in osteoporosis, an antagonist of this cytokine could be beneficial for the treatment of this disease.