Trans-ethnic genome-wide association study of severe COVID-19
oleh: Peng Wu, Lin Ding, Xiaodong Li, Siyang Liu, Fanjun Cheng, Qing He, Mingzhong Xiao, Ping Wu, Hongyan Hou, Minghui Jiang, Pinpin Long, Hao Wang, Linlin Liu, Minghan Qu, Xian Shi, Qin Jiang, Tingting Mo, Wencheng Ding, Yu Fu, Shi Han, Xixiang Huo, Yingchun Zeng, Yana Zhou, Qing Zhang, Jia Ke, Xi Xu, Wei Ni, Zuoyu Shao, Jingzhi Wang, Panhong Liu, Zilong Li, Yan Jin, Fang Zheng, Fang Wang, Lei Liu, Wending Li, Kang Liu, Rong Peng, Xuedan Xu, Yuhui Lin, Hui Gao, Limei Shi, Ziyue Geng, Xuanwen Mu, Yu Yan, Kai Wang, Degang Wu, Xingjie Hao, Shanshan Cheng, Gaokun Qiu, Huan Guo, Kezhen Li, Gang Chen, Ziyong Sun, Xihong Lin, Xin Jin, Feng Wang, Chaoyang Sun, Chaolong Wang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Chaolong Wang and colleagues report a large genome-wide association study for COVID-19 severity in Chinese individuals. By meta-analysis with European data, they identify 3 loci associated with severe disease that suggest key roles for the adaptive immune system and the ABO blood group system in development of severe COVID-19.