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Determinants of synapse diversity revealed by super-resolution quantal transmission and active zone imaging
oleh: Zachary L. Newman, Dariya Bakshinskaya, Ryan Schultz, Samuel J. Kenny, Seonah Moon, Krisha Aghi, Cherise Stanley, Nadia Marnani, Rachel Li, Julia Bleier, Ke Xu, Ehud Y. Isacoff
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Super-resolution quantal imaging relates transmission at excitatory synapses to presynaptic molecular composition. The authors find that evoked transmission varies greatly between synapses and is uncorrelated and physically separate from spontaneous transmission, and identify responsible presynaptic proteins.