Fine-scale Identification of the Most Likely Source of a Human Plague Infection
oleh: Rebecca E. Colman, Amy J. Vogler, Jennifer L. Lowell, Kenneth L. Gage, Christina Morway, Pamela J. Reynolds, Paul Ettestad, Paul Keim, Michael Y. Kosoy, David M. Wagner
| Format: | Article |
|---|---|
| Diterbitkan: | Centers for Disease Control and Prevention 2009-10-01 |
Deskripsi
We describe an analytic approach to provide fine-scale discrimination among multiple infection source hypotheses. This approach uses mutation-rate data for rapidly evolving multiple locus variable-number tandem repeat loci in probabilistic models to identify the most likely source. We illustrate the utility of this approach using data from a North American human plague investigation.